Katharine Isabelle (born March 10, 1982) is the stage name of Katharine Murray, a Canadian actress, born in Vancouver, British Columbia. Her father Graham Murray is a production designer who has won two Emmys for his work on The X-Files, her mother Gail Murray is a Vancouver writer/producer. She is the sister of actor Joshua Murray.

Katharine has appeared in various Canadian and American movies and television series.

At the age of seven she had a role in the motion picture Cousins (1989), starring Ted Danson and Isabella Rossellini. She co-starred with Emily Perkins in Ginger Snaps (2000). The movie was followed by Ginger Snaps 2: Unleashed (2004) and Ginger Snaps Back (2004). Katharine and the five years older Emily went to the same school and were born in the same hospital.