What About Bob? is a 1991 comedy movie directed by Frank Oz which stars Richard Dreyfuss and Bill Murray. Bill Murray plays Bob Wiley, a multiphobic obsessive compulsive psychiatric patient who follows his successful and egotistical psychiatrist Dr. Leo Marvin, played by Richard Dreyfuss, on vacation. When the unstable Bob befriends the other members of the Marvin clan, it slowly drives Leo insane. Other characters include Fay Marvin, played by Julie Hagerty, Anna Marvin, played by Kathryn Erbe, Sigmund "Siggy" Marvin, played by Charlie Korsmo and Mr. and Mrs. Guttman, played by Tom Aldredge and Susan Willis.

Upon seeing his performance at the world premiere, Steven Spielberg spent $250,000 on a campaign to not only get Bill Murray nominated for the Best Leading Actor Academy Award but actually win it. Murray didn't receive a nomination and he on several occasions has attempted to pay Spielberg back, but Spielberg refused.

Bill Murray improvised so many lines during the movie that accurate scripts couldn't be written until after shooting the scenes.

This film is number 98 on Bravo's "100 Funniest Movies".

When Dr. Leo Marvin, a trained psychiatrist, leaves his work to go on vacation in New Hampshire, he leaves his newly published book, "Baby Steps," with his patient, Bob Wiley. Bob is a neurotic person, nearly paralyzed by multiple phobias, and his previous psychiatrist, Dr. Carswell Fendsterwald, looking close to a nervous breakdown, is quitting his practice for a while and leaving town to get away from Bob. This and the fact that a number of psychiatrists have dropped Bob foreshadow future events, though not in the way one would expect.

Bob is afraid he can’t make it without his doctor and fakes his own death to find out where he went for vacation. He takes a bus to New Hampshire and arrives at a gas station, where he begins frantically calling Leo's name. Leo, not happy with Bob visiting him, tells him to get on the bus and go back home. Bob refuses and follows Leo to his vacation home, helped by the Guttmans, the local couple whose house Leo had bought for one down payment -- their dreamhouse, for which they had worked a lifetime.

Leo's family is happy to have Bob with them, but Leo is not. Bob's presence causes a number of events that wrack Leo's characteristic calm demeanor and leave him deeply unsettled. Several of these events occur when Bob begins hanging out with Leo's two kids, Anna and Sigmund. Anna is a typical teenage girl, distraught over having to deal with a father that communicates with her through psychological aides (eg. hand-puppets fashioned in the image of her and her father)and who simply wants to have a good time like Bob. Sigmund, on the other hand, is quite obviously the son of a psychologist; he believes that he has lost his childhood, and has an obsessive fixation with the inevitability of death. Bob seems to become a father figure to the kids, helping Sigmund gain enough confidence to dive into the water (a feat Leo was not able to do, which leads him to push Bob into the lake himself),and forcing Leo to admit to his daughter that he is "Fun... kind of." Other notable events include Bob creating a very awkward tension during the family's dinner, and then imposing upon them to spend the night (in Leo's "Jammies") when a storm rolls in.

Leo has an interview with Good Morning America, so he tries his hardest to get rid of Bob. Bob ends up staying, because the producers of the show think that it will be a great idea for a patient to be on with Leo. The interview is disastrous for Leo, who makes a fool of himself while Bob completely steals the show and everyone's hearts. After Good Morning America leaves, Leo becomes infuriated and takes Bob to an institution. Bob heads in, wondering why Leo isn't coming with him. Leo heads back home, happy that he is finally free. As soon as he arrives, though, he gets a phone call from the institution. Leo heads back, only to find Bob telling tons of jokes to the doctors. Leo ends up taking Bob back, dumping him in the middle of the road. Leo then gets a speeding ticket and his car breaks down, while Bob gets a ride back to the house. Leo fixes his car and heads back home, only to be surprised by a birthday party. His beloved sister Lily from Chicago had come to see him, but this is ruined when Bob appears and puts his arm around her. The sight of Bob with Lily is the final straw, and Leo goes insane and tackles Bob to the ground. (Bob isn't hurt though, and is still clueless to how hostile Leo has become towards him). Leo, having FINALLY had enough of Bob ruining his vacation, breaks into an ammunition shop and steals 20 pounds of explosives. He takes Bob into the woods in the middle of the night and ties him up, strapping the explosives around his body. ("Death therapy, Bob. Guaranteed cure.") Leo abandons him, thinking he is free at last. His happiness is ruined once again when Bob takes Leo's words literally and has an epiphany about his problems, solving them as he breaks free and returns to Leo and his family at the dock with Leo's birthday cake, claiming that Leo's "therapy" cured him. Unfortunately, Bob placed the bags full of dynamite in Leo's huge house, blowing it to pieces.

Leo, having suffered more than he can bear from Bob, becomes catatonic and is temporarily institutionalized. Meanwhile, Bob marries Leo's sister Lily. Leo recovers his senses just after Lily and Bob are pronounced husband and wife by screaming "NO!", though that fact is lost in the fact his family is glad to have him back.

A title card appears in the end that says:

"Bob went back to school and became a psychologist. He then wrote a huge best seller, Death Therapy.

Leo is suing him for the rights."

The movie was filmed in and around the town of Moneta in Virginia located on Smith Mountain Lake. Production had to go south because at the real Lake Winnipesaukee in New Hampshire, the leaves were already turning for the Fall season.

The house used in the filming still stands. The exploding house was a studio miniature.

The local institute which Leo tries to commit Bob in is actually the local Elks Home for retirees in the nearby town of Bedford, Virginia.