Cry-Baby is a 1990 musical directed by John Waters. It stars Johnny Depp as 1950s teen rebel Wade "Cry-Baby" Walker, and also features an expansive cast that includes Iggy Pop, Traci Lords, Ricki Lake, David Nelson, Susan Tyrrell and Patty Hearst. This film did not achieve high audience numbers in its initial release but has subsequently become a cult movie.

The film is a parody of teen musicals such as Grease, of Elvis Presley movies, and of 1950s 'juvenile delinquent' movies. (Johnny Depp has said more than once that he took the role to poke fun at the teen-idol hysteria surrounding him during his days on the TV show 21 Jump Street.) It centers on a group of delinquents named the Drapes and their interaction with the rest of the town and its other subculture, the Squares, in 1950s Baltimore. "Cry-Baby" Walker, a Drape, and Allison, a Square, create upheaval and turmoil in their town by breaking the subculture taboos and falling in love. The movie shows what the young couple have to overcome to be together & how their actions effect the rest of the town.

Part of the film takes place at the now-closed Enchanted Forest amusement park in Ellicott City, Maryland.

The film is rated PG-13 in the U.S. It was Waters' second mainstream Hollywood picture, after his earlier R- and X-rated independent films. The first was Hairspray.

Cry-Baby will be the second of Waters' films to be adapted for the stage as a musical comedy (following Hairspray). It is being produced at the La Jolla Playhouse (California) as part of their 2007 Season, as well as being shadow-cast at the Nuart Theatre by Sins O' the Flesh.

Cry-Baby, the stage musical, has its world premiere at the La Jolla Playhouse on November 6, 2007, running until December 16, 2007. The book is by Mark O'Donnell and Thomas Meehan and the music is by Adam Schlesinger with lyrics by David Javerbaum. The musical is directed by Mark Brokaw with choreography by Rob Ashford. The cast includes Harriet Harris, Carly Jibson, and James Snyder as "Cry-Baby".

A March 2008 opening on Broadway at a theatre to be announced is targeted with an official opening in April.

In John Waters' second mainstream motion picture at a PG-13 rating, Wade "Cry-Baby" Walker (Johnny Depp) is a greaser (or "drape" in Baltimore slang of the time) who falls in love with "square" Allison Vernon-Williams (Amy Locane). Her grandmother (Polly Bergen) and boyfriend Baldwin (Stephen Mailer) are disgusted with her love for Cry-Baby. Meanwhile, Cry-Baby's sister Pepper (Ricki Lake) is pregnant while taking care of two other children. The film co-stars Susan Tyrell as Ramona, Cry-Baby and Pepper's grandmother, Iggy Pop as their Uncle Belvedere, Kim McGuire as drape Mona "Hatchet-Face" Malnorowski, Traci Lords as sexually-active drape Wanda Woodward, Darren E. Burrows as Hatchet's boyfriend Milton Hackett, and Kim Webb as Lenora Frigid, a tramp-ish drape obsessed with Cry-Baby.